Thursday, September 8, 2022

This drug can neutralize three BA.4/BA.5 subvariants, which should be monitored

 Research, editing : Gan Yung Chyan, KUCINTA SETIA

News on disease control, U.S., CCP, Taiwan

News (1)

This drug can neutralize three BA.4/BA.5 subvariants, which should be monitored

A group of experts from Peking University, National Institutes for Food and Drug Control (NIFDC), Beijing Dital Hospital, Capital Medical University have discovered that the drug Bebtelovimab can detect and neutralize multiple BA.4 and BA.5 subvariants with R346 mutations (R346I, R346T, R346S). Their studies are published in preprint form by bioRxiv, an open access reposity for research hosted by Cold Spring Harbor Laboratory.

Sunney Xie Xiaoliang of Peking University revealed that the experts have done studies on the potency of approved neutralizing antibody drugs including 11 monoclonal antibodies and 4 cocktails such as Bebtelovimab, Evusheld, REGEN-COV and Sotrovimab. Only the potency of Bebtelovimab is guaranted. Bebtelovimab is the "only surviving BAb drug" approved by the U.S. Food and Drug Administration (FDA).

Image credit : Eli Lilly/LinkedIn

Bebtelovimab, the monoclonal antibody treatment from Eli Lilly & Company (above), is granted Emergency Use Authorization (EUA) by FDA in February 2022 to fight against the Omicron variant.

The experts found that Evusheld, made up of Tixagevimab and Cilganvimab, has completely lost its efficacy as BA.4/BA.5 with R346I, R346T and R346S completely escapes the detection by Cilgavimab. These R346 mutations also reduce the neutralizing activity of REGEN-COV (Casirivimab and Imdevimab) due to the decreased reactivity of Imdevimab against R346-mutated sublineages.

So is the potency of Sotrovimab further reduced by these R346 sublineages.

R346 is an important immunogenic residue and R346 mutations are found to be able to escape a large group of neutralizing antibodies.

News (2)

Sinovac vaccine not effective against R346 sublineages

The experts also discover that individuals who received triple doses of Sinovac covi vaccine CoronaVac without infection showed 1.5 to 1.7-fold decrease in 50% neutralization titers (NT50) against BA.4/BA.5 with R346I (BA.5.9), R346T (BA.4.6 and BF.7) and R346S (BA.4.7).

News (3)

After breakthrough infection comes subvariant evasion

The experts declare BA.5.9, BA.4.6 and BA.4.7 could significantly evade neutralization by plasma samples from BA.5 breakthrough infection. They measure the neutralizing titers of plasma samples against these SARS-CoV-2(covi) BA.4/BA.5 subvariants, which are obtained from vaccinated individuals without covi infection or with BA.1/BA.2/BA.5 breakthrough infection.

BA.5.9, BA.4.6 and BA.4.7 on the spoke glycoprotein have been identified in various countries including CCP China and the U.S. BA.4.6 harbours R346T, BA.4.7 harbours R346S while BA.5.9 harbours R346I. These subvariants exhibit growth advantages compared to BA.5 and BA.5.

News (4)

Emergence and rapid spread of BA.5.9, BA.4.6 and BA.4.7

The decreased neutralization titers of the plasma samples from BA.5 breakthrough-infection convalescents indicate worrisome potential reinfection of BA.4.6/BA.4.7 and BA.5.9 after recovery from BA.4/BA.5 infection.

The experts call for close monitoring of these subvariants.


News (5)

Covi lasts far into the future

The fact that each new covi strain is more infectious than the previous one is one reason to expect that the virus  lasts far into the future, having already lasted longer than the 1918 Spanish flu pandemic. Scientists are concerned that covi keeps evolving in ways that may prove worrisome.

 

Covid epidemic coordinator Dr. Ashish Jha of White House said on Tuesday (6 September 2022) that the illness is here for the rest of humans’ lives.


Getting new treatments, and not just relying on better vaccines, are ways to go to fight against the evolving covid virus.


Ref: https://www.marketwatch.com/story/research-finds-latest-omicron-variant-ba-4-6-is-better-at-evading-immune-system-than-ba-5-as-scientists-say-covid-will-be-with-us-for-a-long-time-11662560928?mod=search_headline


News (6)

Authorized use areas of Bebtelovimab

According to Eli Lilly, Bebtelovimab is authorized for use under EUA for the treatment of mild-to-moderate covid on adults and pediatric patients (12 years of age and older weighing at least 40 kg) including patients with positive covi testing results, who are at high risk of hospitalization or death and for whom alternate covid treatment options approved or authorized by FDA are not accessible or clinically inappropriate.

News (7)

Limitations of authorized use of Bebtelovimab

In practice, Bebtelovimab is not authorized for use on covid patients who are hospitalized, who require oxygen therapy, respiratory support due to covid or require an increase in baseline oxygen flow rate and/or respiratory support due to covid and are on chronic oxygen therapy and/or respiratory support due to underlying non-covid related comorbidity.

News (8)

Adverse events from monoclonal antibody treatments

According to Eli Lilly, serious hypersensitivity reactions, including anaphylaxis, have been observed with administration of other covi monoclonal antibodies and could occur with administration of Bebtelovimab. If signs and symptoms of a clinically significant hypersensitivity reaction or anaphylaxis occur, immediately discontinue administration, and initiate appropriate medications and/or supportive care. 

Infusion-related reactions, which may occur up to 24 hours after the injection, have been observed in clinical trials of Bebtelovimab when administered with other monoclonal antibodies and may occur with use of Bebtelovimab alone. These reactions may be severe or life threatening. Signs and symptoms of infusion-related reactions may include fever, difficulty breathing, reduced oxygen saturation, chills, fatigue, arrhythmia (e.g. atrial fibrillation, sinus tachycardia, bradycardia), chest pain or discomfort, weakness, altered mental status, nausea, headache, bronchospasm, hypotension, hypertension, angioedema, throat irritation, rash including urticaria, pruritus, myalgia, vasovagal reactions (e.g. pre-syncope, syncope), dizziness, and diaphoresis.

Hypersensitivity reactions occurring more than 24 hours after the injection have also been reported with the use of covi monoclonal antibodies under EUA. 

News (9)

Clinical worsening after monoclonal antibody administration 

According to Eli Lilly, clinical worsening of covid patients after administration of covi monoclonal antibody treatment has been reported and may include signs or symptoms of fever, hypoxia or increased respiratory difficulty, arrhythmia (e.g., atrial fibrillation, sinus tachycardia, bradycardia), fatigue, and altered mental status. Some of these events required hospitalization. It is not known if these events were related to covi monoclonal antibody use or were due to progression of the disease. 

News (10)

Adverse reactions after receiving Bebtelovimab reported

Adverse reactions observed in those who have received Bebtelovimab alone or in combination with Bamlanivimab and Etesevimab, at the authorized dose or higher are infusion-related reactions (n=2, 0.3%), pruritus (n=2, 0.3%) and rash (n=5, 0.8%). The most common treatment-emergent adverse events observed in subjects treated with Bebtelovimab, alone or in combination with Bamlanivimab and Etesevimab, at the authorized dose or higher included nausea (0.8%) and vomiting (0.7%). 

Therefore, not only vaccine injuries and vaccine adverse reactions need to be monitored, adverse events and reactions from monoclonal antibody administration need to be monitored as well. Drugs used in curing covid patients or preventing covid have their own limitations.

Bebtelovimab (LY-CoV1404; LY3853113) is a neutralizing IgG1 monoclonal antibody (mAb) directed against the spike protein of SARS-CoV-2 that maintains binding and neutralizing activity across currently known and reported variants of concern, including Omicron and BA.2. It is being studied for the treatment of mild-to-moderate covid both as a monotherapy and together with other mAbs. Lilly has licensed and developed Bebtelovimab after it was discovered by AbCellera and the scientists at the National Institute of Allergy and Infectious Diseases (NIAID) Vaccine Research Center. 


News (11)

National Health Commission: In areas where there is no epidemic, normalized nucleic acid testing should be carried out as required

The Joint Epidemic Prevention and Control Mechanism of the State Council held a press conference in the afternoon of 8 September 2022 to introduce the scientific and accurate prevention and control of the epidemic. At the meeting, a reporter asked, "At present, many cities and many places are adopting normalized nucleic acid testing, and some places will use nucleic acid testing. Frequency reduced from 7 days to 72 hours. How can we better supervise the standardized operations of nucleic acid testing institutions? How to do nucleic acid testing in places where there is no epidemic?

Li Dachuan, deputy director of the Medical Administration Bureau of the National Health Commission, said that the National Health  Commission attaches great importance to the quality management of nucleic acid testing, and has established a standardized system for the examination and approval of nucleic acid testing institutions, personnel qualification management and quality control and evaluation, and implemented the whole-process supervision of nucleic acid detection. Specifically, a lot of work has been carried out in strict management of nucleic acid testing institutions and personnel qualifications, standardization of sample collection, preservation and transfer, and increased supervision and management in daily and emergency situations. At the same time, the frequency of quality control and quality assessment of the laboratory is encrypted, and the implementation of the withdrawal mechanism for nucleic acid testing is focused on strengthening. Implement the "traffic light" system for nucleic acid testing institutions, and implement green light priority approval for eligible organizers. At the same time, resolutely implement the yellow light rectification and red light exit mechanism. Local health departments should implement the above requirements, strengthen the supervision of nucleic acid testing institutions, give warnings, notify criticisms, cancel nucleic acid testing qualifications, and even revoke the "Medical Institution Practicing License" and other penalties for different violations to ensure the quality of nucleic acid testing.

For areas where no epidemic has occurred, normalized nucleic acid testing should be carried out in accordance with the requirements of the ninth edition of the prevention and control plan, and epidemic monitoring and early warning are carried out.

News (12)

Self-slap in the face, the National Health Commission said that the epidemic-free areas should also be bombarded with normalized nucleic acid testing

Editor : Jing Zhongming / https://www.ntdtv.com/gb/2022/09/08/a103521716.html / Image : The CCP’s National Health Commission slapped itself in the face, and Chinese netizens scolded. (Webpage Screenshot)

自打脸 卫健委称无疫地区也要常态化测核酸挨轰


The 20th National Congress of the Communist Party of China is approaching, officials strengthen "epidemic prevention" for Biaozhong. An official from the Chinese Communist Party's National Health Commission said that normalized nucleic acid testing should also be implemented in non-epidemic areas, contradicting the agency's statement in June, Chinese netizens scolded the Commission.

At the press conference of the Joint Epidemic Prevention and Control Mechanism of the State Council of the Communist Party of China on 8 September 2022, Wu Liang, deputy director of the National Health Commission’s Bureau of Disease Control and Prevention, announced that from 10 September to 31 October, five “strengthening and optimization” will be implemented. "Prevention and control measures", including encouraging no travel during holidays, showing negative nucleic acid certificates when traveling and entering and leaving public places, implementing "on-the-ground inspections" across provinces, and reducing "unnecessary gatherings", etc.

Wu Liang said the move was to ensure that there would be no "local large-scale epidemic" around the Mid-Autumn Festival and the "November"  but the outside world believes that the authorities are more concerned about the "security" of the 20th National Congress of the Communist Party of China.

At the press conference on 8 September, Li Dachuan, deputy director of the National Health Commission's Medical Administration Bureau, said in response to a question from a reporter from People's Daily that for areas where no epidemic has occurred, it is also necessary to "follow the requirements of the ninth edition of the prevention and control plan. Carry out normalized nucleic acid testing.”

Hubei women are copied directly without nucleic acid. pic.twitter.com/JFv9SA05W8

— View of the World (@yunyunfengfeng) September 8, 2022

After the CCP implemented the "Novel Coronavirus Pneumonia Prevention and Control Plan (Ninth Edition)" on 28 June 2022, many places canceled the normalized nucleic acid testing or extended the testing frequency according to the plan. On 9 June 2022, He Qinghua, a first-level inspector of the National Health Commission's Bureau of Disease Control and Prevention, publicly declared that "nucleic acid inspection should not become the norm" in areas where there is no epidemic and rebound risk. The CCP media has also made a big report on this claim.

Now the National Health Commission has changed its tune and said that "normalized nucleic acid testing should also be carried out in non-epidemic areas", triggering a rebound among mainland netizens. Netizens have criticized the government for reneging on its promises in the comments section of Weibo-related news. Some netizens questioned the nucleic acid testing company and CCP officials, "It's been three years, and I still haven't made enough money?" Some netizens also left a message saying, "But are you living a normal life?" "Have the ability to solidify the nationwide lockdown."


Image : Screenshot of Weibo user comments.


News (13)

National Health Commission: Promote nucleic acid "on-the-ground inspection" throughout the National Day holiday and around the country, dynamic clearing remains default

According to CCTV News, on 8 September 2022, Wu Liangyou, deputy director of the National Health Commission’s Bureau of Disease Control and Prevention, introduced at a press conference on the joint prevention and control mechanism of the State Council that the current covid pandemic  is still at a high level, and the Omicron subvariants has become main epidemic strains, China's foreign defense input pressure continues to increase. 

The domestic epidemic situation is still spreading in many places and frequently occurs in many places. The Mid-Autumn Festival and National Day holidays in 2022 are approaching, and the mobility of personnel will increase, which increases the risk of epidemic transmission, and the prevention and control situation is severe and complicated. 

In order to ensure that no large-scale local epidemic occurs around the Mid-Autumn Festival and National Day, minimize the impact on the production and life of the people, and allow the people to spend a healthy, safe and peaceful holiday, in accordance with the work deployment of the State Council's joint prevention and control mechanism, adhere to the general strategy of “preventing imports and preventing internal rebound” and the general policy of “dynamic clearing” remain unswerving, adhere to scientific, precise and strict epidemic prevention and control, and on the basis of fully implementing the ninth edition of the prevention and control plan, strengthen and optimize a series of prevention and control policies and measures.

Celebrate public holidays locally

The first is to advocate for the masses to celebrate the National Day holiday locally, minimize cross-city travel, and avoid the risk of epidemic spread caused by large-scale movement of people.

Safe and orderly travel

The second is safe and orderly travel. Passengers must hold a negative nucleic acid test certificate within 48 hours to board flights, high-speed rail, train, inter-provincial long-distance passenger buses, inter-provincial passenger ships and other means of transportation.

Collect nucleic acid and leave voluntarily for free

The third is to promote "on-the-ground inspection". In accordance with the principle of "collect and leave voluntarily for free, without restrictions on movement", after arriving at the destination, inter-provincial migrants will actively cooperate with the local to complete the "on-the-ground inspection".

Check the valid nucleic acid test negative certificate

The fourth is to check the valid nucleic acid test negative certificate. When checking into hotels and other crowded places such as tourist attractions, the health code and the negative nucleic acid test certificates from other provincial districts and cities within 72 hours must be checked.


News (14)

Navarro's new book reveals why Republicans lost the White House

Reporter : Xiao Jing / Editor : Lin Qing / https://www.ntdtv.com/gb/2022/09/08/a103521617.html / Image : On 31 August 2022, former White House trade adviser Peter Navarro appeared in Washington District Court for a hearing. (Alex Wong/Getty Images)

纳瓦罗新书揭示“我们为何失去白宫?”

Former White House trade adviser Peter Navarro said that poor personnel appointments are doomed to failure of the Trump administration.

"I call it the Achilles' Heel of my boss. I love this boss despite all these bad arrangements. He's the best president we've ever had," Navarro said in a statement. He said in a recent interview with the English-language New Tang Dynasty Television (NTD) program "Capitol Report".

He also said that Trump's 2020 presidential campaign must not be repeated in a possible 2024 presidential bid.

Navarro is sharing content from his new book, Taking Back Trump's America: Why We Lost the White House and How We'll Win. The book will be published on 20 September 2022.

In his book, Navarro wrote about how Trump, soon after becoming elected, began surrounding himself with “globalists, Never-Trump Republicans, wild-eyed [House] Freedom Caucus nut jobs,” and “Wall Street transactionalists,” who would “come to plant so many poisonous Bad Policy Trees” during his administration.

Navarro said he was one of three senior advisers who stayed with Trump during the 2016 campaign until the handover. He was "relentless" when he commented on Trump's mistakes in personnel choices.

In the interview, Navarro cited Trump's first secretary of state, Rex Tillerson and Secretary of Defense Jim Mattis, as examples of Trump's "stupid choices," This will be part of what he calls a "clown cabinet".

According to his book, Tillerson and Mattis had opposed Trump's efforts to renegotiate a trade deal with South Korea, arguing that doing so could undermine "delicate military calculations" or "diplomatic alliances" between the two countries.

Despite their opposition, Trump and then-South Korean President Moon Jae-in signed a revised free trade agreement in September 2018 that was welcomed by U.S. automakers and meat exporters.

Trump has said the old deal, approved by Congress in 2011 and taking effect the following year, was a "terrible deal" by Hillary Clinton, who, as secretary of state in the Obama administration, pushed for the final version of the trade pact.

The U.S. trade deficit with South Korea increased from $16.7 billion in 2012 to $27.7 billion in 2016, according to the U.S. Trade Office.

China policy

One of the "people who have never met Trump" that Navarro mentions in his book is Steven Mnuchin, the Trump administration's former Treasury secretary.

Navarro said that Mnuchin and Trump's son-in-law, Jared Kushner, "single-handedly destroyed" Trump's China policy, "with Wall Street and the Chinese Communist Party behind the scenes."

"They're just doing it to make their nest fuller," Navarro said.

Navarro wrote in his book that when Trump asked to label China a currency manipulator, Mnuchin "always refused." Finally, on 5 August  2019, Mnuchin agreed to put this label on the CCP.

However, Navarro said it was too late. He explained in the book that if Mnuchin had agreed to designate China in January 2017, it would "directly and accurately strike one of China's worst abuses" and it would provide U.S. officials " a valuable bargaining chip with China in trade negotiations."

The U.S. Treasury Department revoked the designation on 13 January 2020, two days before Trump and Chinese Vice Premier Liu He signed the Phase 1 trade deal.

China has not fulfilled its commitments in the trade deal. According to the Peterson Institute for International Economics (PIIE), China only buys 57 percent of its promised U.S. exports.

“The reality of that deal was the skinny deal. That’s what it was,” Navarro told NTD. “It was a pale shadow of what it should have done.”

Navarro said Kushner was at fault for the bad trade deal.
“He was double-dealing with Steve Schwarzman on Wall Street and John Thornton, these guys, along with the Chinese Communist Party negotiators, behind the backs of me and [former U.S. Trade Representative Robert] Lighthizer, and even the president to come up with this bad deal,” Navarro said.
Schwarzman is the chief executive officer of U.S.-based investment firm The Blackstone Group, and Thornton is the executive chairman of Canada-based mining company Barrick Gold and a former Goldman Sachs president.

If Trump becomes president again, Navarro suggested the United States should decouple from China.

“I can assure you one of the first things he’s going to do … is lockout tariffs on Communist China,” Navarro said. “We’ll just cut the cord from them because every dollar we pay at Walmart for made-in-China, made-in-Communist-China product, it goes into their military war machine to take out Taiwan.”

“I think it’s really important if we’re going to win back the White House 2024, that we govern over the next four years in a way which gets things done,” Navarro continued. “Time is precious, when you’re in the White House, as we learned, and there were things we left on the table that I wish we hadn’t.”
The Epoch Times has reached out to Mattis, Mnuchin, Kushner, Schwarzman and Thornton for comment.
News (15)

F-35 fighter jets contain Chinese materials, the United States suspends reception, analyzes the supply chain

Reorters : Wang Guanlin and Zhang Dongxu / https://www.ntdtv.com/gb/2022/09/09/a103521960.html

The U.S. Department of Defense said it was suspending deliveries of new F-35 fighter jets because a magnet for the engine used materials from China; the contractor said an alternative source had been found. The Department of Defense and manufacturers are conducting a broader analysis of the supply chain.

Vertical take-off and landing on amphibious assault ships, short take-off and landing from the ground, fifth-generation stealth fighter F-35, users include the U.S. Air Force, Navy, Marine Corps, and counterparts of ten other countries such as Japan, NATO allies; Deputy Secretary of Defense Stephen Bryen submitted a letter in 2020, suggesting to lease F-35s to Taiwan and train Taiwanese pilots on behalf of them in response to threats from the CCP.

The U.S. Department of Defense said on 7 September that it had suspended deliveries of new F-35 fighter jets because a magnet in a turbine engine was made of unauthorized cobalt and samarium alloy materials from China, violating U.S. Purchases Law.

The fighters were built by Lockheed Martin, and the turbines were produced by Honeywell. DOD's F-35 Joint Program Office states that it has confirmed that "the magnet will not transmit information or compromise the integrity of the F-35 and there are no performance, quality or safety risks associated with this issue"; the contractor identified problem to the Ministry of Defense that was then proactively informed, and an alternative source of the alloy was found.

"The magnet cannot see or come into contact with any sensitive program information," Lockheed Martin said in a statement. The report quoted a person familiar with the issue as saying that the Defense Department's F-35 Joint Program Office, The Defense Contracts Administration, and Lockheed Martin are meeting daily to conduct a broader analysis of the supply chain.

News (16)

Does Wang Qishan influence the top 20 card slots? Inventory of the changes in the fate of the vice chairman of the Communist Party of China

Reporter : Li Enzhen / Editor: Wen Hui / https://www.ntdtv.com/gb/2022/09/08/a103521244.html


王岐山影响二十大卡位?盘点中共副主席命运变迁


The 20th National Congress of the Communist Party of China is approaching, and high-level personnel cards have become the focus of outside attention. Some analysts believe that whether the 74-year-old vice president of the Communist Party of China Wang Qishan will step down next year, who will Xi Jinping choose as his deputy, or who will have an impact on the personnel arrangements of the 20th Congress.

The 20th National Congress of the Communist Party of China will be held on 16 October. Public opinion generally believes that Xi Jinping will be re-elected. Among the members of the Politburo Standing Committee, Li Keqiang will go and stay, Li Zhanshu, Wang Huning, and Han Zheng will step down. Who will replace them? This series of personnel arrangements is expected to affect the power infighting among the high-level factions of the CCP.

In addition, Wang Qishan's departure or stay will also have an impact on Xi Jinping's personnel arrangements.

Wang Qishan served as a member of the Standing Committee of the Political Bureau and Secretary of the Central Commission for Discipline Inspection after the 18th National Congress of the Communist Party of China in 2012. After resigning in 2017, he served as the vice chairman of the Communist Party of China and has no position within the party and is second only to the seven members of the Politburo Standing Committee. Therefore, the outside world calls it the Eighth Standing Committee of the Communist Party of China.

In June 2022, Wang Qishan was elected as the representative of the 20th National Congress of the Communist Party of China in Jiangsu Province. In 2018, the CCP amended the constitution and abolished the limitation that the term of office of the president and vice-chairman should not exceed two terms. According to this stipulation, Wang Qishan has a reason to continue to be re-elected after the 20th National Congress of the Communist Party of China, just like Xi Jinping.

On 8 September, a commentary in Hong Kong's "Ming Pao" stated that Wang Qishan is expected to step down from office next year. Who will be his successor? Whether the future vice-chairman will be a member of the Politburo or maintain his status as an outsider will have an impact on the personnel arrangements of the Twenty Congress. The article takes stock of the changes in the status of successive vice-chairmen.

Since 1954, the first vice-chairman of the Communist Party of China was Zhu De, who was second only to Mao Zedong at that time; after the "Cultural Revolution", when Liu Shaoqi, the then president, stepped down, Soong Ching Ling and Dong Biwu served as vice-chairmen but they were only acting presidents.

In 1975, the positions of the Chinese president and vice-chairman were abolished. In 1982, he was reinstated as president of the country.

The article stated that the first vice-chairman who was restored after the "Cultural Revolution" was ill-fated. The original nominee, 75-year-old Politburo member and director of the Hong Kong and Macau Affairs Office Liao Chengzhi, died suddenly during the "two sessions" and was replaced by 77-year-old Ulanfu. After Ulanfu resigned, the 80-year-old veteran Wang Zhen served as the vice chairman; after Wang Zhen resigned, he was succeeded by the red capitalist Rong Yiren.

After Rong Yiren, the vice-chairmen of the Communist Party of China were all concurrently held by members of the Politburo Standing Committee and executive secretary of the Secretariat of the CPC Central Committee. They were Hu Jintao, Zeng Qinghong and Xi Jinping. Hu and Xi were both successors and held real power.

After Li Yuanchao became vice-chairman, he was only a member of the Politburo, and the position was only at the level of deputy national level. Until Wang Qishan took over, the Wang Zhen model of vice chairman was restored, and the position returned to the national level.

The article believes that at the 20th National Congress of the Communist Party of China, if the vice chairman of the state is in the Wang Zhen and Wang Qishan model, there is no need to occupy the Politburo seats, and the political life of the elders can continue; ; The most unlikely to appear is the Hu and Xi model, because it is difficult for a successor to appear in this session.

On 8 September, current affairs commentator Yue Shan told NTDTV that Wang Qishan will be over 74 in March next year, and he is unlikely to renew his post. Who will replace Wang Qishan? If the Wang Qishan model continues, and a current Politburo Standing Committee member and member become Xi's deputy after being dismissed from party affairs, then Li Keqiang, Li Zhanshu, Wang Yang, Han Zheng, and Liu He are all possible but Han Zheng has a Jiang faction background, and Li Keqiang may have had enough and may choose to withdraw altogether.

At present, in addition to the internal political worries of the CCP, there are also repeated outbreaks of the epidemic. The Chinese economy continues to decline, natural and man-made disasters continue, and social grievances are boiling, which will have an impact on the 20th National Congress of the Communist Party of China.

Current affairs commentator Wang He wrote in The Epoch Times that the CCP is currently facing considerable external shocks. First, the CCP announced that the 20th National Congress of the Communist Party of China will coincide with the rebound of the epidemic, and the national epidemic distribution map is red. If the epidemic is out of control, the "Twenty National Congress" will be postponed (the national "two sessions" in 2020 will be postponed to May of that year), and the big one will be postponed indefinitely. Second, the "dynamic clearing" has hit the economy hard, and people's grievances are boiling. More than 400 million people have publicly announced their withdrawal from the CCP and its affiliated organizations ("Three Exits"), and CCP China is approaching the critical point of "changing the sky".


News (17)

Chengdu continues to lock down, the time of unblocking is unknown, Apple suppliers may be affected

Before the 20th National Congress of the Communist Party of China, the epidemic broke out in many places, and more than 70 cities were locked down The Chengdu Municipal Government, with a population of 21.192 million, announced on the 1st that it will conduct nucleic acid tests for all staff for 4 consecutive days from the 1st, and all residents will stay at home in principle. Chengdu is locked down. "Nikkei Shimbun" on 7 September 2022 reported that due to the continuous "dynamic clearing" of Chengdu, Apple suppliers Foxconn, BOE, etc. will be affected.

News (18)

Japanese muscadine seedlings flow into China, with an annual loss of 10 billion yen

Mainland "Sunshine Rose" grapes have been harvested one after another to seize the Mid-Autumn Festival market. However, this kind of grape actually entered China from Japan in 2016. The prototype is the seedling of Japanese muscadine grape. It is said that the planting area in China is 30 times that of Japan. Japanese officials say this has cost Japan 10 billion yen a year. A new policy is currently being formulated to strictly prevent the illegal outflow of new varieties of agricultural products.

News (19)

WeChat notifies overseas users that personal data will be sent back to CCP

Recently, a large number of overseas WeChat users have been notified that if they accept the WeChat service agreement, their personal information will be sent back to the domestic server in CCP China. A French YouTuber was shocked and disturbed and advised overseas Chinese to abandon WeChat. Experts pointed out that WeChat Yitian intended to set up an international version and a domestic version in order to prevaricate overseas infringement allegations but the fact has never stopped acting as a thug for the CCP's speech censorship. Jurists are calling on Western countries to legislate to ban Chinese apps to prevent the CCP from monitoring long-arm intrusions.

News (20)

Are Chinese-made drones passive? Baykar: Look back when they are near the border of CCP China

The Turkish TB2 drone has repeatedly helped Ukraine defend against the Russian army and became famous in the first battle. Haluk Bayraktar, CEO of TB2 drone maker Baykar Technology, told Japanese media that drones will play a key role in conflicts in the future, including a possible war in the Taiwan Strait. He also revealed that an official from a country that purchased Chinese drones had heard that once the Chinese drones approached the Chinese border, they would fly in the opposite direction, and he suspected that the software settings would avoid approaching the CCP’s airspace. This is really "totally unacceptable".

News (21)

Rainie Yang's seafood discussion provoked experts, the CCP used her to unite the front against Taiwan

Reporter : Ruili / https://www.ntdtv.com/gb/2022/09/09/a103521813.html / Image of Rainie Yang : Video Screenshot


Taiwanese artist Rainie Yang recently said in a Chinese variety show that she "hasn't eaten any seafood in Taiwan", which caused controversy. Commentators believe that if Taiwanese artists want to have a market in China, they must conform to the CCP's "patriotic formula."

Taiwanese singer Rainie Yang said, "Actually, I haven't eaten any seafood in Taiwan. In my early years, my family was under a lot of economic pressure. In fact, eating seafood is a luxury there."

Taiwanese singer Rainie Yang, recently in the cultural communication program "There are Poems and Faraways" of the Propaganda Department of the Zhejiang Provincial Party Committee of the Communist Party of China, took the initiative to mention "I am from Guangdong", and even said "Actually, I have never eaten any seafood in Taiwan." Eating seafood "is a luxury" in Taiwan has sparked controversy.

Rainie Yang participated in many shows in China after marrying Chinese artist Li Ronghao in 2019. This will inevitably disappoint Taiwanese fans, who accused Rainie of deliberately abandoning Taiwan in order to earn RMB.

Tang Hao, an international affairs commentator: "Eating seafood is a luxury in Taiwan, which surprises me because it's very different from the Taiwan I've seen."

Immediately after the video went viral, many netizens came out and posted photos of Rainie Yang eating seafood, trying to help Rainie Yang "restore her memory".

Some netizens also speculated that she might want to express that her family was relatively difficult when she was a child, so seafood seemed expensive, and she did not mean to belittle Taiwan. However, it is also true that the subtitles added by the CCP's official media have turned "Taiwan" into "Taiwan, China" and other small actions, intending to use this artiste to carry out united front work against Taiwan.

Subsequently, Rainie Yang urgently shut down the message functions of Facebook and IG to avoid being screened by dissatisfied netizens.

Commentators believe that nowadays Taiwanese or overseas artists must conform to a set of CCP's "patriotic formulas" if they want to stand out in the Chinese entertainment industry.

These include "self-denying overseas identity", "depreciating overseas life experience", "loving and praising the motherland", "cooperating with political correctness and telling lies" and so on.

Tang Hao, an international affairs commentator, said, "Like I have a famous Taiwanese friend who once thought about the development of the Chinese TV industry, but after two trips, she decided to give up the Chinese market. I asked her why? She said, there a lot of things are too fake, and there are a lot of unreasonable rules. Even someone like her who is often on TV and will cooperate with the effect of the show can't accept it. Like to think outside the box."

As of press time, Rainie Yang has not yet responded to the seafood incident, but as early as August, she closed the message function for reposting the post "There is only one China in the world" on Weibo, which was criticized by Taiwanese netizens.

News (22)

To eat or not to eat? Maine lobster on "red no-eat list"


 A few days ago, the American "Seafood Watch" organization announced that American lobster was listed as "avoidance" seafood. This sparked strong dissatisfaction in the lobster state, Maine.

"Seafood Watch" under the Monterey Bay Aquarium in California is an authoritative organization about seafood. Thousands of catering companies use the food recommendations given by Seafood Watch as a basis for decision-making on seafood products.

On 5 September 2022, "Seafood Watch" gave a heartbreaking report for North American lobster lovers, putting 14 fish farms in the United States and Canada into a red rating, asking to "avoid" the purchase of seafood from these fish farms, including the Maine fishing grounds that mainly fish for lobster.

Seafood Watch pointed out that the vertical line fishing gear used in these fishing grounds can entangle endangered North Atlantic right whales, of which there are fewer than 340 left in the world.

The report sparked outrage among Maine officials and fishermen.

In a statement, Maine Governor Janet Mills accused Seafood Watch of misleading consumers and businesses and ignoring the efforts of generations of Maine fishermen to protect the sustainability of the lobster fishery. She noted that no right whales have died in Maine gear and that there has been no gear entanglement in 18 years.

Maine Senator King even tweeted that the report was "outrageous" and would cause great harm to the state.

However, different companies have different practices on whether to continue to buy lobster. Some U.S. businesses, including HelloFresh, have followed the recommendation to remove lobster from menus. Companies such as Whole Foods said they would not stop selling lobster for now.

News (23) to (26) /  Reporter : Luo Tingting / Editor: Wen Hui / https://www.ntdtv.com/gb/2022/09/09/a103521922.html


News (23)

U.S. security adviser warns: CCP's armed invasion of Taiwan is a "'certain threat"

Image : U.S. National Security Adviser Sullivan at a news conference on 11 July 2022. (Chip Somodevilla/Getty Images)

美国安顾问示警:中共武力侵台是“确切威胁”


The situation in the Taiwan Strait continues to be tense. U.S. National Security Adviser Sullivan warned that the CCP's military invasion of Taiwan is a "certain threat". He is discussing a new bill with Congress, and the United States will strengthen Taiwan firm support.

News (24)

Sullivan: There may be military emergencies around Taiwan

Bloomberg broadcasted a preview of a TV interview with Jake Sullivan on 7 September 2022. He said that the CCP has not given up on using force to invade Taiwan to achieve reunification, so military incidents around Taiwan are still a “definite threat.”

"I think there is still a definite threat that there may be a military emergency around Taiwan," Sullivan said.

Sullivan said that the CCP's recent military activities have undermined the peace and stability of the situation in the Taiwan Strait, while the United States' stance on the Taiwan issue has always been firm, that is, "there can be no unilateral changes to the status quo across the Taiwan Strait."

"We will continue to push back against any use of force to change the status quo," he stressed.

News (25)

U.S. Congress proposes new bill to deepen US-Taiwan alliance

Sullivan said in an exclusive interview that he will discuss a large, bipartisan bill with U.S. congressmen that night, the Taiwan Policy Act of 2022.

The bill, co-sponsored by Senate Foreign Affairs Committee Chairman Bob Menendez, a Democrat, and Senator Lindsey Graham, a Republican, will be considered before the committee on 14 September.

The bill made important changes to the Taiwan Relations Act, which has guided U.S.-Taiwan relations over the years, including defining Taiwan as a "non-NATO ally", providing Taiwan with military funds including $6.5 billion, and promoting Taiwan's ability to defend itself.

The bill will also rename the Taipei Economic and Cultural Representative Office in the U.S. to the "Taiwan Representative Office" and promote higher-level exchanges between U.S. and Taiwan officials.

In addition, the bill proposes to impose sanctions on Chinese officials responsible for intensifying Taiwan-Strait relations.

Sullivan said the bill can effectively improve Taiwan's security, "very effective and solid in terms of how we can enhance our security assistance to Taiwan."

Foreign Affairs Committee Chairman Bob Menendez and Republican Senator Lindsey Graham said in a statement jointly introducing the bill that the bill is the most comprehensive restructuring of U.S. policy toward Taiwan.

“As Beijing continues to seek to coerce and isolate Taiwan, there should be no doubt or ambiguity about the depth and intensity of our resolve to stand with the people of Taiwan and their democracy,” Menendez said.

Taiwan's Foreign Ministry spokesman Ou Jiangan said at a press conference on 8 September that the proposal of this large-scale pro-Taiwan bill by heavyweight U.S. lawmakers from both parties demonstrates the firm support of the United States for Taiwan. Taiwan expresses its high welcome and sincere thanks for this.

The CCP regime reacted violently to the bill. Liu Pengyu, a spokesman for the CCP embassy in the United States, threatened the U.S. Congress to "stop advancing the case," claiming that it would take so-called "countermeasures."

News (26)

Taiwan has become an anti-communist "check-in place", US and French dignitaries have visited Taiwan one after another

The United States does not take the threat of the CCP seriously. Since the US House of Representatives Speaker Nancy Pelosi ignored the threat of the CCP and made a high-profile visit to Taiwan on 2 August 2022, dignitaries from many countries have successively visited Taiwan.

Stephanie Murphy, vice chairman of the Intelligence and Special Operations Group of the U.S. House of Representatives Armed Services Committee, led eight bipartisan congressmen to visit Taiwan and met with Tsai Ing-wen at the presidential palace in the morning of the 8th.

The Taiwan Presidential Office stated that Murphy's delegation is the sixth US delegation to visit Taiwan after the CCP's military exercise in early August, demonstrating the importance and support of the United States to Taiwan from the local government to the federal government, from the executive branch to the Congress.

Tsai Ing-wen thanked the U.S. congressman for his visit, a move that demonstrates the U.S. Congress' rock-solid support for Taiwan.

In addition, a delegation of five French parliamentarians led by Cyril Pellevat, vice chairman of the French Senate European Affairs Committee, also arrived in Taipei on 7 September. On the 8th, the delegation met with Taiwan Vice President Lai Ching-teh, President of the Legislative Yuan You Xikun and others.

Zhong Zhidong, an assistant researcher at the National Security Research Institute of the Taiwan Institute of National Defense Security, told Radio Free Asia: "After Pelosi's visit to Taiwan, China (CCP) suppressed Taiwan, making Taiwan a political figure from all over the world protesting against China (CCP) and anti-CCP 'punch card'. There will be more and more visiting groups.”

News (27) to (30) / Host : Qin Peng / Publisher : Qin Peng Observations, Qin Peng Live / https://www.epochtimes.com/gb/22/9/8/n13820314.htm【秦鹏直播】官员抢递投名状 民喊“20饿饿年”

News (27)

Chengdu staged a hot pot feast, many cities shouted hungry, hungry

Two years ago, on 8 September 2020, the Communist Party of China held a national commendation conference for fighting against the covid epidemic. Xi Jinping put a big gold chain on Zhong Nanshan and others, and expressed his gratitude to Zhong Nanshan and others. The world announced: China has won.

In his nearly 10,000-word speech at the time, Xi Jinping kept referring to "struggle" and "continuously winning struggles with new historical characteristics", but the name of the whistleblower Li Wenliang was not mentioned once. All those who investigate the truth of the epidemic have nothing to do with the title of hero. Citizen reporters Zhang Zhan, Chen Qiushi, and Fang Bin were still in prison at the time, and their lives and deaths are unknown.

Two full years have passed. The countries around the world that were ridiculed by the CCP at that time, after the arrival of the Omicron variant, which is only as harmful as the big flu, rely on scientific epidemic prevention, and have already gotten out of the panic and ban. This even includes North Korea, which lacks medical treatment and medicine next door, and also announced a victory in the fight against the epidemic a few days ago.

On the contrary, it is China itself, the epidemic situation is still one after another, and the only tactic adopted is the same set that became famous in the first battle - the lockdown of cities. In the latest wave of city lockdowns after the CCP announced the convening of the 20th National Congress, more than 70 cities are under partial or full lockdown, affecting more than 300 million people.

Today, let's take a look at the real situation of some cities that flow out of the Internet.

In Guiyang, the capital of Guizhou Province, with a population of 6 million, there is Guiyang Huaguoyuan, the largest community in Asia with a total population of 500,000, and residents have run out of food. At 3 am, residents who had been hungry for several days collectively shouted. 

Some netizens asked, "When we only eat vegetables in 4 days, want to know what government officials have eaten?"

In Yili, Xinjiang, netizens reported that it has been blocked for 40 days so far. In the midst of the authorities' strict speech ban, many people risked their lives to send out information, saying that "the (pregnant) stillbirth, the old man hanged, the five children with a 40-degree fever community shirk their responsibilities, and the five-year-old child was not delivered in time. Doctors lost their lives." The locals said, "How can I keep getting deleted, banned, called, and restricted by regions." Some netizens who can access the Internet send private messages to other strange netizens without any hope, hoping to be seen. "I just want to repost and increase exposure. Today's Yili is similar to Shanghai in the past."

Some people also reported, "Our family is fine, my dad can still buy some food when he becomes a volunteer but the supplies are not enough", "I can't believe that I live in the 21st century in 2022, and I can't believe that there will be a famine. There will be people who won't be able to eat."

At the same time, netizens reported that "the vegetables, fruits, and meat donated by the counties in Ili were sold to us at high prices, and the naan made by the farmers' uncles and aunts were sold to us at high prices. If they were not sold, they would be left to mold and rot."

While asking for help, these netizens were also full of fear, "I'm really grateful that baby can see it, I don't need to post Weibo, I'm really scared. After this post is sent, I will delete the private message myself. of."

Even so, the measures of the local government in Yili are still increasing. A community notice said that in order to zero-contact volunteers, each unit is required to "begin to seal the door of the residents with tape, and seal the door of the unit with tape, and continue after the silence tomorrow. Sealed and controlled, residents prepare ropes at home", use ropes to "sample garbage, materials, including nucleic acids, and hang them from windows with ropes", "tear sheets without ropes".

This scene is so absurd that many people doubt whether it is true. However, from the super words of Yili, you can see the name of the community, and some netizens in Jiangsu said, "I traveled to Xinjiang in August and was trapped in Wujiaqu. Having experienced the quarantine policy in Xinjiang, it is really much stricter than inland, and I feel a little bit inhuman.

People in many cities were crying out for hunger. There was an old man who ended his life early by hanging himself after being hungry for a few days!

News (28)

Netizens made a picture for 2022: 20 Hungry, Hungry Years

Of course, all this just now, we cannot see it in the official propaganda of the CCP. The latest official news is that the Chinese Communist Party donated 400 million RMB to the flood disaster in Pakistan, and the Pakistani Prime Minister expressed his gratitude. At the same time, officials issued an announcement to the Chinese public asking for donations to the Luding earthquake-stricken area.

Such absurdity reminds me of the famous Chinese writer Lao She's sentence "I want to write the saddest tragedy, which is full of shameless laughter".

In Chengdu, which was declared "silent" for three days, more than 20 million people are still silent. The day the ban will be lifted is far away. However, a local netizen's hot pot feast became popular. Let's take a look.

News (29)

The officials of various provinces and cities submitted their nominations. Ministry of Foreign Affairs: 90% of the people are satisfied

Everyone knows that the harm of Omicron is actually very low. Zhang Wenhong previously released a large sample of more than 30,000 people (33,816) to prove that the mortality rate of people without underlying diseases is 0. After it was published in the weekly newspaper "CHINA CDC WEEKLY", it was deleted, and then Gao Fu, director of the China Center for Disease Control and Prevention, was dismissed.

On 7 September, Huatai Securities released a blockbuster research report, saying that “the death rate of overseas variants of the covi may be lower than that of influenza virus.” The news caused many online cheers, believing that the epidemic was coming to an end, but the relevant reports were soon deleted.

According to the report, as of the first week of September, the 7-day average number of newly diagnosed cases in Indonesia, Thailand, and Vietnam was less than 30 per million, less than one-tenth of the peak since the beginning of the year; In South Korea and Hong Kong, China 7 days, the number of newly diagnosed cases is about 1,300 to 1,600 per million people, which is only 20% of the peak since the beginning of the year; the number of newly diagnosed cases in Japan has also peaked and declined. In general, the upward "slope" and total scale of the number of newly diagnosed cases in this round of the epidemic are significantly lower than those at the beginning of the year.

Therefore, starting in September, South Korea announced the cancellation of nucleic acid requirements for entry, Singapore cancelled its entry epidemic prevention policies including vaccines/quarantine, and Japan raised the daily limit of entry to 50,000.

However, the CCP authorities are still doing the opposite. On 8 September 2022, the National Health Commission of the Communist Party of China stated that normalized nucleic acid testing should also be carried out in areas where no epidemics have occurred.

However the Internet has memories. Netizens turned to the request of the National Health Commission of the Communist Party of China on 9 June. The official said at the time that "for areas where there is no epidemic and no risk of importation, nucleic acid inspection should not become the norm."

Netizen Rong Jian questioned: "You keep saying this over and over again, which one is the truth? How can the common people believe you?!"

Some netizens mocked the CCP's tone and said, "We need a 'Ministry of Truth' in '1984'. It specializes in erasing and tampering with historical records to prevent the public from inquiring about the bound edition."

Some netizens responded bluntly, "They no longer need to believe it or not. As long as others obey, it is best that they don't have the awareness and ability to think independently."

In recent days, when the city was locked down on a large scale, there have been many brutal scenes of residents being handcuffed by the police because they refused to do nucleic acid testing.

At the same time, some local governments have issued donation proposals to the society because they have no money to make nucleic acids.

On the one hand, hundreds of millions of people have been repeatedly banned, unable to go to work and do business normally, and all industries have withered. More and more people are feeling miserable. On the other hand, the authorities have increased their restrictions again, requiring regular testing in places where no epidemic has occurred. Obviously, this displeased quite a few people.

To this end, Hu Xijin, came out again to put out the fire for the official. He said, "Some people will argue: if you let go, it will be over. Others say that as long as the nucleic acid is there, the epidemic will never end, and that the nucleic acid interest groups have kidnapped the country. These are bullshit, or deliberately created conspiracies. I'm sure that with such a major national policy, no force can 'hijack' the country's decision-making. How can those nucleic acid companies like Sansha have such power? What the Internet and real estate giants can't do, Can they do it?"

Unexpectedly, Hu Xijin's words were praised by many people. Twitter netizen @大耳鳥mei said, "If there is no one who speaks, there are these nucleic acid companies. He can make these companies disappear in a blink of an eye."

I agree with this view because the CCP's anti-epidemic policy for the past three years has always been directed and deployed by Xi Jinping himself. Therefore, the current CCP Health Commission, as well as the provinces and cities, are actually flattering Xi Jinping by abusing their own residents.

This approach is very similar to those bandits and robbers in the past. Before joining Liangshan, they had to kill a person as a certificate to show other bandits and robbers that they would stand with the underworld boss in the future. . Since everyone has done bad things, there is no need to worry that you will betray him.

Some people may think that I insult the heroes of Liangshan by saying this. However, the CCP's gangsters have indeed been adopting this gangland model, forcing political campaigns to persecute the people time and time again, so that every participating official and worker has blood on their hands. Only in this way can those evil persecution continue and has yet to be truly rehabilitated. For example, under the command of Mao Zedong, Deng Xiaoping directly led the anti-rightist movement, so Deng Xiaoping refused to admit that the anti-rightist movement was wrong in the end.

The same is true of the Cultural Revolution. The officials of the CCP at that time all participated in the persecution of other people, so they insisted on the three-seven and June-four attacks against Mao Zedong. The CCP’s suppression of the student movement in 1989 and the CCP’s persecution of Falun Gong in 1999 were similar. They all used political campaigns to force every official to participate, and even allowed a large number of “610” officials, police, soldiers, doctors, and patients to participate in live organ harvesting. In this way, few people dare to expose the truth.

Now, this kind of inhumane zero-covid policy is of no exception. Those who oppose and those who are not active participants will be hit, and those officials who have brutally tossed the residents of their own jurisdictions will be promoted and commended. For example, in the past two days, the Shanghai Municipal Health Commission's Center for Disease Control and Prevention was listed as a "community of civil servants satisfied by the people", which was ridiculed by netizens. Because it was the tragedy of Shanghai's lockdown that made countless people feel that there were no eggs under the nest, which further stimulated a huge wave of immigrants.

However, many people did not notice that this commendation was actually directed and deployed by the Party Central Committee headed by Xi Jinping. Xinhua News Agency reported on 30 August 2022 that the National Commendation Conference for "civil servants satisfied by the people" and "collective public servants satisfied by the people" was held in Beijing on the morning of the 30th. General Secretary of the CPC Central Committee, President of the State, and Chairman of the Central Military Commission Xi Jinping cordially met with the commended representatives, extended sincere greetings and warm congratulations to them, and encouraged them to keep their mission and responsibility in mind and act bravely.

Therefore, I think those people in China who are starving, unable to work, and their businesses are closed due to city lockdowns, nucleic acid testing, etc., must sober up and not think that these are just the work of local officials, or that capital has kidnapped local policies. On the contrary, all of this has never escaped the vision and control of the highest authorities of the CCP.

That is to say, all the evils are actually done by CCP in the end.

Last night, when Mr. Lan Shu and I participated in the Voice of Hope dialogue, we discussed a question together: Why did the Communist Party of the Soviet Union disintegrate long ago, while the Communist Party of China is still raging? Our views are very consistent. It is because many Chinese people are still confused and are just defending their rights but they do not realize that the root cause of China's disaster is the rule of the Chinese Communist Party, which leads to the fact that the Chinese Communist Party is still doing evil.

Therefore, China must wake up, recognize the CCP, oppose the CCP, and disintegrate the CCP. Only in this way can this boundless disaster be completely ended.

On 7 September, Mao Ning, a new spokesperson for the CCP Foreign Ministry, said at a press conference that the Chinese people’s satisfaction with CCP and the government has exceeded 90% for 10 consecutive years.

News (30)

More than 400 million resignations from the CCP, a new China without the CCP is near

However public opinion under a dictatorship is false. Take a look at the frequent rollovers under the major news of the CCP, and see that the number of people who have quit the CCP, regiments, and teams in the world has exceeded 400 million recently, and then look back at Saddam, Ceausescu and others before their downfall. Long live the mountain, I believe the still water flows deep, and the magma is silent when the magma is rushing underground before the volcano erupts. As the CCP continues to intensify its efforts, a new China without the CCP is not far away.










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