Saturday, February 22, 2020

China researchers : Wuhan Huanan Seafood Market is not the origin of COVID-19

Publisher, 22 February 2020 : China News Service, Kunming
Ref : http://www.chinanews.com/sh/2020/02-22/9100907.shtml
English Translation : Gan Yung Chyan
                                  / KUCINTA SETIA


Image by _freakwave_ from Pixabay : COVID-19 is now an international concern. 


According to the official website of the Xishuangbanna Tropical Botanical Garden, the park under management by the Chinese Academy of Sciences together with the South China Agricultural University and Beijing Brain Center collected 93 virus (SARS-CoV-2 / covi, in short) samples shared globally in the GISAID EpiFluTM database covering 12 countries on four continents. As of 12 February 2020, their analysis of the whole genomic data of the virus samples has revealed that the novel coronavirus from the Huanan Seafood Market in Wuhan was introduced from other places.

The 93 samples contain 58 haplotypes, and the evolutionary relationship shows that the haplotypes H13 and H38 are relatively "old" haplotypes, and pass an intermediate vector (mv1, which may be an ancestral haplotype or may come from an intermediate host Or "patient zero") and is associated with bat coronavirus RaTG13, and haplotype H1 is derived from haplotype H3.

The researchers said that the patient sample haplotypes associated with the seafood market in Wuhan are H1 and its derived haplotypes H2, H8-H12, and one Wuhan sample haplotype H3 has nothing to do with Wuhan Huanan Seafood Market. It can be seen that the novel coronavirus of that seafood market was introduced from other places, and then spread rapidly in the market. In addition, based on the patient's onset time records and population expansion time inference, it also confirms that Wuhan Huanan Seafood Market is not the origin of covi.

In addition, researchers traced the sources of H13 and H38 virus samples to patients from Shenzhen (the first case in Guangdong) and patients in Washington State (the first case in the United States). Their travel records indicate that they were infected in Wuhan from the end of December 2019 to early January 2020. No H13 and H38 haplotypes were detected in the existing Wuhan samples.

The study also shows that the covid outbreak has two significant expansions before 12 February 2020. One is on 8 December 2019, and the results suggest that the virus may have started human-to-human transmission in early December and even late November, and subsequently a full-blown outbreak occurred in Huanan Seafood Market while another virus outbreak expansion occurred on 6 January 2020.

It is worth mentioning that to subdivide the source, the researchers divided 58 haplotypes into five groups, including 3 ancient super communicator haplotypes (H1, H3, and H13) and 2 new super communicator haplotypes H56 and mv2. There are three sources of viruses identified in Guangdong and two sources of viruses in Chongqing and Taiwan. There are more samples in Australia, France, Japan and the United States. Patients have at least two sources of infection, especially the US includes five sources. Of particular concern is the haplotype of H56, a super-spreader, and a source of infection for patients in Australia, France, the United States and Taiwan.

Studies have also shown that no recombination event occurred in the genome of covi.

Human-to-human transmission of covi started in November 2019

The above news has caused a lively discussion among netizens in China.

Some netizens analyzed that this article pointed out that human-to-human transmission was confirmed before 6 January 2020. All 11 patients infected with COVID-19 (covid, in short) in Wuhan Huanan Seafood Market show human-to-human transmission of covi. However, the official announcement of "human-to-human transmission" was not officially announced until 20 January 2020, which is equivalent to the announcement of "Evidence that Wuhan virus outbreak is a human disaster".

Netizen Freeman commented, "At the beginning of the outbreak, the bandits almost determined that the virus originated from the Huanan Seafood Market. It was thought that the epidemic would soon pass. Anyone who found a scapegoat for the outbreak could shriek responsibility. The virus does not give the bandits any face. The covid outbreak is far more violent than sars, and the duration is not the same as that of sars. Using the South China Seafood Market as a scapegoat is obviously full of loopholes. Since the article of the Chinese Academy of Sciences came out to face, it seems that the source of the virus is coming to light. "

"Forest New" ridiculed, "Someone is laughing in the dark. Study it! I won't admit it."

Earlier, the Communist Party of China has always announced that the source of covi in Wuhan was wild animals sold in the Wuhan Huanan Seafood Market. The official has always avoided the question of who, how and why the vital "Patient Zero" is infected.


However, the internationally authoritative medical journal "The Lancet" published on 24 January 2020 a paper written by nearly 30 Chinese medical and scientific researchers, including Huang Chaolin, Deputy Director of Wuhan Jinyintan Hospital and disclosed that among the first 41 hospitalized cases of covid, only 27 patients have a history of contact with the Huanan Seafood Market, and the patients who first became ill on 1 December 2019 have no history of contact with the Huanan Seafood Market.

Further Ref : 
Banna Botanical Garden analyzes the evolution and spread of SARS-CoV-2 based on genome-wide data, Xishuangbanna Tropical Botanical Garden, Chinese Academy of Sciences,
http://www.xtbg.cas.cn/xwzx/kydt/202002/t20200220_5502619.html

Chinese Academy of Sciences admits seafood market is not the origin of COVID-19. Human-to-human virus transmission begins in November 2019, Reported by Zhu Yin, Edited by Ming Xuan, New Tang Dynasty Television,https://www.ntdtv.com/b5/2020/02/22/a102783383.html

New study further proves Wuhan seafood market not the source of COVID-19, Ecns.cn http://www.ecns.cn/news/sci-tech/2020-02-23/detail-ifztvsqr0576579.shtml

COVID-19 | SARS-CoV-2 Coronavirus Portal
https://globalbiodefense.com/novel-coronavirus-covid-19-portal/

StayGate's Notes:
In layman terms, covi is in use for the virus SARS-CoV-2 in COVID-19 while covid is in short for the contagious disease scientifically known as COVID-19.

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