Wednesday, February 19, 2020

Why did some Wuhan pneumonia patients suddenly fall to the ground?

Writer : Yang Jingduan 
Sub-Editing : Mu Jian
Editor : Li Min
Source : The Epoch Times
Ref : https://www.ntdtv.com/b5/2020/02/18/a102780019.html
English Translation : Gan Yung Chyan
                                 / KUCINTA SETIA

Image : Some Wuhan pneumonia patients died suddenly after falling to the ground, or they were related to the overreaction of the immune system caused by covid infection, which is medically called "cytokine storm". (Video screenshot)


There is a phenomenon in Wuhan pneumonia [ novel coronavirus / novel coronavirus pneumonia / COVID-19 (covid, in short) ]. Some patients suddenly fell to the ground and died. Most of them are young adults who suddenly fell down while working or walking while others lied on the road straight and died, similar to sudden death symptoms. Why were these happening? These may be related to the abnormal immune system of the human body under covid infection. 

Young strong adults suddenly die from COVID-19 or from immune system "out of control"

The human body has a well-functioning immune system that protects against viruses and bacteria.

When a virus or bacteria invades, in order to defend against infection, human cells emit some "cytokines." Cytokines issue instructions to the body's immune mechanisms and immune cells, let immune cells surround bacteria or viruses, and then engulf and destroy germs. In the process of killing the virus, it may cause some inflammatory reactions such as redness, swelling and pain, fever, cough and sputum. When the virus is eliminated, people recover. This is a disease-resistant way with normal immune function.

It is easy to understand that many elderly or frail people have relatively low immune function, are prone to be infected with covid, and have a high mortality rate. However, some young and middle-aged people come quickly and fiercely when they die. In fact, this is the immune response going to the other extreme and out of control.

This immune out-of-control phenomenon, known by the technical term "cytokine storm", is when the body is infected with a virus, it emits excessive amounts of cytokines and a large number of immune substances causing inflammatory reactions. These substances are not only powerful at killing viruses and bacteria, but also can destroy various organs of the body.

When an excessive immune response hurts blood vessels, causing the loss of blood and body fluids, a serious phenomenon occurs, called "septic shock." The patient's blood pressure dropped rapidly and suddenly fell. If a severe inflammatory reaction occurs around the trachea, causing a small airway blockage, the person will be severely hypoxic, and hypoxic coma or death will occur.



Caused by covid infection, the overreaction of the immune system, also known as the "cytokine storm," can lead to swift death. (Shutterstock)

Therefore, whether it is low immune function or hyperactive immune function, it may bring danger. Only when the body's inflammatory response and the two forces controlling the inflammatory response are balanced can the immune function work properly and kill the virus.

Some young people have genetic factors in the cause of hyperimmunity. For example, some people have defects in the gamma interferon gene, which leads to excessive production of interferons; others produce a large amount of interleukins, tumour necrosis factors, and chemokines. These cytokines have strong bactericidal and virus-killing capabilities, but if they are produced in excess, they may cause serious damage to systemic organs such as the lungs, kidneys and heart. In addition, smoking or malnutrition is also a risk factor.

Cytokine storms caused by covid

Cytokine storms are thought to be the leading cause of death in Spain in the early part of the last century, recent bird flu and SARS. With the sudden occurrence of sudden death of young adults in Wuhan virus, the cytokine storm has once again become the focus of research and medical staff.

Different viruses cause abnormal immune system reactions with varying degrees of severity

Recently, an article published in the "The Lancet" magazine analyzed the cytokine storms induced by SARS, Middle East Respiratory Syndrome Virus (MERS) and covid, and found that the severity of cytokine storms caused by covid is severe and far more than previous viruses. This shows covid is very fierce, very toxic, and even more alarming.

In addition to sudden death, many patients die within a short time after diagnosis, which may be related to cytokine storms.


About the Author:

Yang Jingduan is the founder and medical director of the Yang's Integrated Medical Centre in Pennsylvania, a professor at the University of Arizona Integrated Medical Center, and the chairman of the American College of Clinical Acupuncture. Born in a family of traditional Chinese medicine, he has been invited to give lectures at Harvard University, University of Pennsylvania, Baylor College of Medicine, and American Psychiatry Annual Meeting.

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