Four reasons for suspecting Wuhan virus lab in the eye of the pandemic

Publisher  : New Tang Dynasty Television
Ref : https://www.ntdtv.com/b5/2020/02/06/a102771302.html
English Translation by : Gan Yung Chyan
                                      / KUCINTA SETIA

The Wuhan Institute of Virology has applied for a patent for Remdesivir, a drug developed for the treatment of novel coronavirus pneumonia (Wuhan pneumonia). This move surprised the outside world, and once again set their sights on this institute, that was seriously questioned as the source of the virus. What role does the institute play in this pandemic? Why was it involved in the eye of the pandemic over the origin of the virus?

In the evening of 4 February 2020, the official website of the Wuhan Institute of Virology claimed that “Chinese scholars have made important progress in the screening of new anti-coronavirus drugs in 2019”, on the drug Remdesivir that has not yet been marketed in China, and “on 21 January, a Chinese invention patent (anti-2019 new coronavirus use) will enter major global countries through the Patent Cooperation Agreement (PCT). "

Many people were surprised by the infringement. Remdesivir is a new type of experimental broad-spectrum antiviral drug developed by Gilead Corporation of the United States, which is believed to effectively inhibit the replication of SARS and MERS viruses in respiratory epithelial cells. The use of this drug in the United States has successfully cured a Wuhan pneumonia patient. It was then provided free of charge to China for the treatment of novel coronavirus. The drug is currently undergoing clinical trials at the Beijing China-Japan Friendship Hospital.

Upon hearing the news of Wuhan Institute of Virology, a Gilead spokesperson responded to Free Asia in an email saying that Gilead was aware of the Wuhan Virus Research Institute's application for a "use patent." Remdesivir is a drug developed by Gilead and has patents in China, including Gilead's application for a "use patent" for use against new coronaviruses.

Gilead said the immediate priority is to determine as soon as possible the potential efficacy of Remdesivir in combating novel coronavirus.

Gilead's point is quite clear. At the moment of the epidemic, it is important to save people. As for the issue of intellectual property, let's put it aside for the time being. Compared with the practice of Wuhan  Institute of Virology, it is unnecessary to say who respects life and who ignores it. The Wuhan Institute of Virology, which was seriously questioned as the source of the virus, did not work hard to fight the epidemic, but it claimed no one could match it. In the words of the common people, "Don't lay eggs hard and actively fight for nests."

Bai Yuezhu, President of Bai's Biotechnology Consulting Company, who is familiar with the patent application process for drugs, said that the application of a "use patent" in the human experimental phase of a drug does not necessarily mean that it will be recognized. "It's not that simple, it doesn't mean you can steal my stuff."

Ding Sheng, Director of the Global Health Drug R & D Center and Dean of the School of Pharmacy of Tsinghua University in Beijing, believes that the application of the Wuhan Institute of Virology is "less likely". Even if it is successfully applied, it does not hold the structure (invention) patent of Remdesivir and cannot be applied. "It's like digging with a shovel. You don't have a shovel in your hand. How do you dig?"

Please note that the Wuhan Institute of Virology claims to have applied for an invention patent on 21 January 2020. On 20 January 2020, two important people came forward. One is the first time that Xi Jinping made a statement about the epidemic situation of novel coronavirus, and the number of cases diagnosed each day increased by a geometric multiple. The other is Zhong Nanshan, who for the first time affirmed the virus can be transmitted from person to person.

According to the Wuhan Institute of Virology, their pharmacodynamic research on the virus was definitely earlier than 20 January because the study of pharmacodynamics does not happen overnight. In other words, while the people of Wuhan did not know that they were at risk of disease transmission, the Wuhan Institute of Virology had already started cell experiments and discovered an effective drug against a new type of coronavirus that had no formal name.

So why didn't Wuhan Institute of Virology take this medicine out to cure and save people? Is it more important to apply for a patent than to cure someone? If the efficacy of the drug has not been determined, why did it preemptively apply for a patent for a drug that is still under verification? This is completely different from their treatment of "Shuanghuanglian Oral Liquid".

On 31 January 2020, the Chinese Academy of Sciences announced that the Shanghai Pharmaceutical Research Institute and Wuhan Virus Research Institute had jointly discovered that the Chinese patent "Shuanghuanglian Oral Liquid" could inhibit the new coronavirus. Then the CCP ’s official media reported in a high profile, causing a surge in buying on the mainland, and in some places it was even sold out.

The Chinese Academy of Sciences made it clear that Shuanghuanglian Oral Liquid is still undergoing clinical research while the Wuhan Institute of Virology and the Shanghai Institute of Materia Medica cannot verify "the release of Shuanghuanglian can suppress the new virus" without evidence.

What does studying synthetic viruses do? Did the virus leak?

Yesterday, Zhengzhou legal person Ren Zhao sent an open letter to Wuhan Institute of Virology, urging them to disclose details of the virus research process. Ren Zhao said that many people had reported the management of the virus institute as "administrative confusion" in real names, and had subsequently deleted posts.

Ren Zhao's application for disclosure includes the following: details of virus preservation and access to this institute from 2019 to 2020, disclosure of research and development details of this institute's research on coronavirus, disclosure of the research and development process of Remdesivir drugs, and patent application detailed documents, public research professor Shi Zhengli's research direction, published papers and detailed resume.

Shi Zhengli posted a post on her personal WeChat circle of friends on 2 February 2020 stating that the novel coronavirus outbreak in 2019 is a punishment to humans for uncivilized living habits by nature. She also stated that she was willing to use "life guarantee” that she “has nothing to do with the laboratory." Even some Western media infiltrated by the Chinese Communist Party have expressed that such suspicions were "fake news”.

However, on 3 February 2020, "Dr. Wu Xiaohua" real-name testified in WeChat that the novel coronavirus was related to the virus leak in Shi Zhengli's laboratory. At present, it is not clear who Wu Xiaohua is. Het may be a medical scholar familiar with the Chinese scientific research system.

Wu Xiaohua bluntly confronted Shi Zhengli openly and raised two key questions about Shi Zhengli.

First, Shi Zhengli's team claims that the novel coronavirus was directly transmitted to humans by bats. Wu Xiaohua believed that this was Shi Zhengli’s lie. According to medical common sense, bat viruses must be mutated to enter the body. This genetic mutation requires the participation of one or two intermediate hosts such as rats or primates, and this genetic modification can only be done in the laboratory. However Shi Zhengli's dissertation did not mention the existence of intermediate hosts at all.

Second, the internal management of Chinese medical laboratories is chaotic. Wu Xiaohua believes that this is the main reason for the virus leak.

In the face of Wu Xiaohua's calling, Shi Zhengli has been silent. We said that there are two possibilities for silence. One is to disdain argument, and the other is acquiescence. Why does Shi keep silent on the matter?

In addition, some netizens dug up a research paper co-authored by Shi Zhengli  in 2015, with the title "A cluster of SARS-like coronaviruses derived from bats, showing the potential for transmission to humans. Words such as "chimeric virus", "hybrid virus", "synthetic virus" and "does not depend on other necessary adaptive mutations on its natural backbone" appear many times in the paper.

The WeChat account "Voices of Workers and Peasants" stated that the original text was published in an electronic journal of the internationally renowned journal Nature Medicine. "Voices of workers and peasants" said that the original text was English, and all he cited were from Baidu translation. And given the original article link (https://www.nature.com/articles/nm.3985?fbcldi=lwAROiTTfDIT-uxNFPtvQH-xFrF6QaF1hKE1Ey2TPrEi17XfFUIbpUIAosDc), the publication time of the article is 9 November 2015, and corrections done on 6 April 2016.

The paper reads, "In order to study the possibility of circulating bat coronavirus (that is, the possibility of infecting humans), we constructed a chimeric virus" and said "this hybrid virus allows us to evaluate this new The ability of spinous protein to cause disease ". It also said," Based on this, we synthesized an infectious full-length SHC014 recombinant virus and demonstrated its ability to replicate in vivo and in vitro. "

Simon Wain-Hobson, a virologist at the Pasteur Institute in Paris, says researchers have created a new type of virus that "if the virus escapes, no one can predict its trajectory."

People want to know why the research is so risky. What is the point of such an experiment? What is a synthetic virus for?

Laboratory animals sold by Wuhan Virus? Caused by a virus leak?

Third, on the day before yesterday (4 February), Xu Bo, chairman of China's Duoyi Network, stated on Weibo that he brought reliable evidence as a clue and reported it to Wuhan Institute of Virology. Xu Bo, while listing some basic facts, attached multiple evidence links to Shi Zhengli's dissertation.

Xu Bo said that because the epidemic prevention is very important, it is suspected that the Wuhan Institute of Virology's mismanagement of laboratory animals caused viral laboratory animals to flow out, resulting in a new coronavirus outbreak in 2019. He also emphasized, "I clearly think that the transgenic virus developed by Shi Zhengli for humans in 2015 is different from Wuhan novel Coronavirus but there must be a lot of other similar viruses in his laboratory, and there must be continued research on similar viruses in the future. It is the truth that should be investigated. "

This question has always been a question of people demanding the truth. Many media, including news stories, have listed a lot of facts, suspecting that the virus may have flowed out of the Institute.

However, Richard H. Ebright, a biologist at Rutgers University in the United States, said yesterday that although there is no evidence that the virus has been artificially modified based on the current genome sequencing of the virus, "this does not not mean that the possibility of the virus from this epidemic entering the population due to laboratory accidents can be completely ruled out. "

Let's return to Xu Bo's Weibo. He suspects that the Wuhan Institute of Virology "has mismanaged laboratory animals and caused virus lab animals to flow out."

This statement is not airless. On 2 January, the Intermediate Court of Songyuan City, Jilin Province, sentenced Li Ning to 12 years in prison. He was charged with "a total of more than RMB 37.56 million in scientific research funding for corruption, of which 10.17 million was obtained from sales of laboratories to eliminate animals and milk."

Li Ning is a professor at China Agricultural University and is known as the "youngest academician". In his judgment, there was such a paragraph. "From July 2008 to February 2012, during the research process, related subjects purchased scientific research funds to purchase pigs and cattle required for the experiment, and the sales of the subjects eliminated during the research process were eliminated. The defendant Zhang Lei asked Li Ning for instructions on how to deal with the proceeds from pigs, cows, and milk. Li Ning instructed Zhang Lei to hand it over to two accountants by surnames of Ou and Xie, who then deposited the sum into a personal bank card with a cumulative amount of RMB 10,179,201.86. "

The description of this verdict tells people clearly that the genetically modified scientist sold the laboratory's genetically modified pigs, cattle and genetically modified milk for more than 10 million yuan.

To whom were these animals and milk sold to? Were they consumed? Do they carry virus or germs? Why didn't the laboratory treat these experimental products harmlessly? Is there any such laboratory in China that is quietly selling laboratory animals?

Fourth, in the news highlights on 28 January, we quoted the news from France. French government officials said that the China Communist Party quietly built a number of laboratories similar to the Wuhan P4 laboratory. "Some laboratories are very suspicious."

Former White House chief strategist Bannon said the China Communist Party lied about everything. If novel coronavirus is found to be artificially synthesized, the China Communist Party is over.