Tuesday, August 18, 2020

China successfully develops folic acid-rich eggs

Reporter : Li Chen / Publisher : China Science News

Ref : http://news.sciencenet.cn/htmlnews/2020/8/444316.shtm / Direct translation

Image courtesy : Animal Husbandry Institute

 

Recently, "Food Chemistry" published online the results of folic acid-rich eggs and folic acid form detection methods developed by the high-quality functional animal product innovation team of the Chinese Academy of Agricultural Sciences. The team established a technical system for the production and quality control of folate-rich eggs in the development of the agricultural industry standard of "Folic Acid Fortified Eggs", which provided scientific and technological support for the development of the functional egg industry.

Researcher Zhang Junmin, the chief researcher of the team, introduced that folic acid is an essential micronutrient for the human body. Insufficient intake can easily lead to diseases such as anemia in pregnant women and fetal neural tube defects. Folic acid deficiency is a global problem. The average intake of folic acid in my country is 180.9 μg/d, which is lower than the recommended intake of 400 μg/d by the National Health Commission, and less than 9% of the population with sufficient intake.

Currently, more than 50 countries around the world implement folic acid fortification policies, but most of the commonly used folic acid supplements are oxidized synthetic folic acid. Excessive intake is not good for the human body, and people with methylenetetrahydrofolate reductase polymorphism cannot be effective It is converted into the biologically active form of 5-methyltetrahydrofolate, which cannot be used efficiently. Therefore, the development of folic acid-rich egg production technology and related research on the detection of folic acid form in eggs is of great significance for improving the dietary folic acid level of Chinese residents.

The research aimed at the problem of unclear folic acid enrichment rules in eggs and lack of folic acid form detection technology, and systematically revealed the rules of enrichment of folic acid in eggs at different levels in the diet. The study found that the appropriate enrichment amount is 116 μg/piece, which is more than three times that of ordinary eggs (34 μg/piece), and the folic acid content of one egg can reach 29% of the recommended intake of the National Health Commission.

The team further improved the EMR-Lipid pre-processing method, shortened the sample pre-processing steps and time, and achieved efficient detection of eight forms of folic acid in response to the time-consuming traditional detection methods of folic acid and the inability to achieve simultaneous detection of multiple forms. Studies have found that the folic acid in folate-rich eggs is dominated by the easily absorbed active form of 5-methyltetrahydrofolate (>90%). The above research results show that folic acid-rich eggs can be used as a good dietary source to improve the nutritional status of folic acid in Chinese residents.

The research was supported by the collaborative innovation task of the Science and Technology Innovation Project of the Chinese Academy of Agricultural Sciences, the Science and Technology Innovation Project of the Chinese Academy of Agricultural Sciences, the basic operating expenses of the Beijing Institute of Animal Husbandry, the Chinese Academy of Agricultural Sciences, the Beijing Municipal Natural Science Foundation and the Beijing Municipal Science and Technology Commission.

Related paper information: https://doi.org/10.1016/j.foodchem.2020.127767

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