Sunday, March 1, 2020

Shanghai sequenced the genome of SARS-CoV-2 earlier than Wuhan but its P3 lab is closed

Report : Li Yun
Editor : Li Quan
Publisher : New Tang Dynasty Television
Ref : https://www.ntdtv.com/b5/2020/03/02/a102789553.html
Translation : Gan Yung Chyan
                    / KUCINTA SETIA

Image : STR / AFP Getty Images

The Shanghai P3 Laboratory was closed the day after  the laboratory team publicized the world's first SARS-CoV-2 (covi, in short) genome sequence. The CCP's move was accused of "academic mute." 

The team's research report revealed that covi is most similar to the two virus samples of the Chinese military.

According to Caixin.com and the South China Morning Post on 28 February 2020, a team led by Professor Zhang Yongzhen of Shanghai Public Health Clinical Center and School of Public Health of Fudan University has completed whole gene sequencing on 5 January 2020.

The Shanghai Public Health Center immediately reported to the Shanghai Municipal Health Commission and the National Health Commission and other competent authorities on the same day, reminding them that the new virus is similar to SARS, and it is recommended to take appropriate measures to prevent the spread of the disease, because the patients from which the samples were collected have very serious symptoms.

On 6 January 2020, a secondary emergency response was initiated within the China CDC. But until  11 January, the team did not see a response from the authorities, so the team posted the world's first covi gene sequence on virologic.org.

However, the CCP officials were still telling the Chinese people at that time that Wuhan had no new confirmed cases and no obvious signs of human-to-human transmission since 3 January 2020.

Zhang Yongzhen's team felt that the authorities apparently had no intention to take any action to alert the public about the virus. So they decided to make the genetic sequence of the virus public.

A source close to Zhang Yongzhen's team said, "This is not an individual's disgrace. It is a face of a respiratory disease that was not well known in the past, especially during the Spring Festival, when there was a large population movement."

However, after Zhang Yongzhen's team disclosed the sequence of the new coronavirus gene, the authorities closed the laboratory the next day for "rectification" reasons. The CCP's move was accused of "academic mute."

The source revealed that the Shanghai Public Health Center was temporarily closed, but the authorities did not explain the reason. "We have requested reopening four times, but we have not received a reply."

Closing the laboratory has a major impact on scientists' research as they are racing against time and hope to find a way to control the coronavirus as soon as possible.

It is reported that the Biosafety Level 3 laboratory of the Public Health Center just passed the national annual inspection on 5 January 2020 and received a late approval to study the coronavirus on 24 January 2020. However, the Shanghai Health Commission was ordered to close the laboratory.

According to China Media, the day after Zhang Yongzhen's team published the world's first virus-sequencing gene, a team led by the National Health Commission also released the global shared influenza virus database "[Global Information Assistance Organization]"  where it is indicated there are five other viral genome sequences from different patients.

At that time, the National Health Commission also said that the viral gene sequencing published by Professor Zhang would be shared by WHO. Nan Zao said that this message was later sent to WHO through the officially designated Wuhan Institute of Virology of the Chinese Academy of Sciences.

Outsiders question why the Fudan University laboratory was closed. Considering that Zhang Yongzhen's team is the first Chinese scientific research team to propose that Wuhan virus is most like the Chinese military virus, this "rectification" may not be as simple as publishing the genome sequence without approval. .

Zhang Yongzhen's Shanghai team successfully sequenced the genome of covi on 5 January 2020, two days before the Chinese Communist Party officially announced the discovery of COVID-19 in Wuhan.

Zhang Yongzhen's team also reported the findings to the National Health Commission on the same day, and suggested "relevant defense and control measures" in public places, because the patients from whom the samples were collected had very serious symptoms, and the virus was found on the bat.

On 7 January 2020, Zhang Yongzhen's team submitted a paper to the international academic journal Nature in accordance with genetic sequencing, clearly suggesting that the two types of samples (No. CoVZC45 and CoVZXC21) of SARS-CoV-2 and Zhoushan Bat Virus are most closely related.

Among them, the nucleotide sequence identity of covi and CoVZC45 is 89.1 per cent, and the amino acid similarity of nsp7 and envelope protein (E protein) is 100 per cent. According to public information of Gene Bank, these two samples were uploaded by the Chinese military in 2018.

This conclusion is consistent with the conclusions of the Greek research team and the Guo Media consultant expert team, both of which made inferences that SARS-CoV-2 did not evolve by nature.

Sean Lin, a PhD in microbiology and a former director of the Virology Laboratory at the Walter Reed Army Research Institute in the United States, told The Epoch Times that the E protein remains completely similar when the entire host is transformed, and it is basically impossible to occur naturally.

On 3 February, the day when the research paper of Zhang Yongzhen's team was published, the paper of Shi Zhengli's team of Wuhan Institute of Virology was also published in the journal Nature, claiming that SARS-CoV-2 is similar to the Yunnan bat virus RaTG13 discovered by the institute in 2013.

The covid epidemic has been raging for two months. For this outbreak, many scientists at home and abroad believe that covi is artificially synthesized, and it is suspected that it was artificially synthesized and leaked by the P4 laboratory of Wuhan Institute of Virology.

Xi Jinping emphasized "biosafety" five times in several meetings and requested that the "Biosafety Law" aimed at regulating the application of biotechnology be introduced as soon as possible to speed up the construction of a national biosafety law and regulation system and a system guarantee system. It is believed to indirectly confirm scientists' speculation.

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